Eyedrops
The formulation of eyedrops — from contact lens cleaning and storage solutions to ophthalmic surgical irrigants and therapeutic medications for the eyes — must comply with strict regulatory requirements and product specifications.
Water is the primary component of most eyedrops, and they may also contain salts (such as sodium chloride), preservatives, petrolatum used in ointment production, and gel polymers acting as lubricants. For heat-sensitive eyedrops, sterilization can be achieved through sterile filtration, or heat-sensitive components can be separately sterile-filtered and then added to pre-sterilized ingredients.
Purpose of Separation
● Prefiltration
To reduce particle content and bioburden before sterile filtration.
● Sterile Filtration
Sterile filters must maintain reliable microorganism retention efficiency during extended production processes.
Application Requirements
● Filters must provide stable high flow rates and must be robust enough to handle large-scale production.
● Sterile filters must maintain reliable microorganism retention efficiency during extended production processes.
● Filters should not adsorb preservatives in the product.
Recommended Products
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